medRxiv PreprintsInternational13 November 2026
Patient-Reported Food Noise, Cravings and Appetite in Adults with Obesity Treated with Weekly Injectable GLP-1 Based Therapies: A Prospective Real-World Study
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Aims: Although pivotal trials have established efficacy in weight reduction during the use of GLP-1 based therapies, daily fluctuations in food-related experiences between scheduled assessments remain to be better characterized. We therefore aimed to assess day-to-day patterns in food noise, cravings, hunger, satiety, and fullness among adults receiving weekly semaglutide or tirzepatide for weight management. Materials and Methods: This prospective, direct-to-participant, US observational study enrolled adults receiving weekly subcutaneous semaglutide or tirzepatide for weight management with
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