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medRxiv PreprintsInternational13 November 2026

Oxygen Uptake Efficiency Slope (OUES) and Mortality in Chronic Heart Failure: Comparisons of Absolute and Percent-predicted Values across Different Equations

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Aim: The oxygen uptake efficiency slope (OUES) is a prognostic indicator obtained from cardiopulmonary exercise testing (CPX) in chronic heart failure (CHF) patients. Although various equations exist for calculating predicted OUES, it remains unclear whether absolute or percent-predicted values offer a more accurate prognostic assessment. To investigate and compare mortality prediction in CHF patients using the OUES absolute values or the percent-predicted approach, incorporating the equations of Hollenberg, Buys, and Milani. Methods: Retrospective cohort study involving CHF patients evaluated
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