Middle Temporal Gyrus Neurite Microstructure and Scam Susceptibility in Older Adults Without Dementia

Background: Financial exploitation is a prevalent public health concern among older adults, and emerging evidence links vulnerability to gray matter macrostructure and white matter microstructure, including within brain regions and networks implicated in early Alzheimer's disease. Although diffusion tensor imaging is sensitive to age-related variation in brain microstructure, its scalar metrics cannot distinguish among the tissue properties contributing to observed differences. Neurite orientation dispersion and density imaging (NODDI) models distinct tissue compartments, yielding estimates of

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