Cardiovascular and metabolic trajectories in men engaged in a multidimensional preventive care program: a prospective observational study

Objectives: To describe within-individual changes in cardiometabolic, functional and neuroendocrine markers between two standardized evaluations in men engaged in a structured preventive care program, and to examine transitions across clinical risk categories. Design: Prospective observational cohort study using routinely collected data; paired within-individual analyses. Setting: Single preventive health center in Paris, France, offering a standardized multidisciplinary assessment with individualized lifestyle, supplementation and, when indicated, pharmacological recommendations. Participants

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