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medRxiv PreprintsInternational12 November 2026

Volumetric Analysis of the Deltoid Muscle From Neck-to-Knee Dixon MRI: A pilot population assessment of a posterior intramuscular injection target

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Abstract Background: Deltoid muscle volume varies across anatomical regions and population groups, with potential implications for intramuscular injection site selection. Evidence comparing middle and posterior deltoid volumes in vaccine-eligible populations is limited. Purpose: To compare middle and posterior deltoid muscle volumes by vaccine eligibility group, sex, and side. Methods: Deltoid muscles were manually segmented into anterior, middle and posterior regions in 43 UK Biobank Dixon MRI scans. A MONAI deep learning model trained on the annotations (Dice score = 0.78) segmented deltoid
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