medRxiv PreprintsInternational12 November 2026
Determinants of mpox vaccine acceptance among peri-urban residents in Sekondi-Takoradi, Western Region of Ghana: A community-based cross-sectional study
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Mpox re-emerged as a global public health concern in 2022, and the Western Region of Ghana became the epicentre of the countrys largest recorded outbreak in 2025. Ahead of a sub-national vaccination campaign launched in October 2025, no study had examined the determinants of mpox vaccine acceptance among peri-urban residents of the region using a theoretically grounded framework. This study determined the sociodemographic and Health Belief Model-based determinants of mpox vaccine acceptance among peri-urban residents of the Sekondi-Takoradi Metropolis, Western Region, Ghana. A community-based
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