Unraveling the genetic architecture of the human mammillary bodies

The mammillary bodies are a central component of the hippocampal-diencephalic-cingulate network that is critically involved in emotion processing and memory function, yet their genetic architecture remains unknown. We conducted a genome-wide association study (GWAS) of mammillary body volume in 38,064 participants from the UK Biobank and replicated our findings in the Rhineland Study cohort (N = 4,860). Mammillary body and hypothalamic subregional volumes were derived from structural brain MRIs using FastSurfer-HypVINN, an established and validated deep learning-based segmentation tool. Univar

This content is for informational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Consult a healthcare professional before starting any supplement, treatment, or program: especially if you are pregnant, nursing, taking medication, or managing a health condition.