The effect of carotid atherosclerosis and revascularization on cognition and dementia: a systematic review and meta-analysis

Background: Carotid artery atherosclerosis may accelerate cognitive decline and increase dementia risk, but evidence is fragmented and inconsistent, and benefit of revascularization on cognitive outcomes uncertain. Methods: We systematically searched Medline, Embase, Web of Science, the Cochrane Central Register, and Google Scholar for articles published until 11 November 2024, reporting change in cognition or dementia incidence in relation to carotid artery intima-media thickness, plaque, stenosis, and revascularization procedures. We excluded studies that investigated people with dementia, l

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