medRxiv PreprintsInternational8 November 2026
The development and psychometric evaluation of the Post Activity Symptom Scale (PASS) for Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome.
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Purpose: To develop and psychometrically evaluate a new scale measuring post-exertional malaise in people with myalgic encephalomyelitis (ME)/ chronic fatigue syndrome (CFS). Methods: A draft scale was co-produced with patient and clinician advisory groups. After extensive pilot testing, adults with ME/CFS completed the Post Activity Symptom Scale online and repeated it two weeks later to assess test-retest reliability and sensitivity to change. Rasch analysis assessed each domain for unidimensionality, targeting, internal reliability, item fit and local dependency. Then Rasch-transformed inte
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