Stressful life events recorded in 39.7 million clinical notes: associations with mental disorders, comorbidity, and frailty

Abstract Background: Despite being harmful to both mental and physical health, stressful life events are not recorded in structured electronic health records. They appear sporadically in narrative clinical notes, where they are difficult to analyze at scale. Natural language processing (NLP) has made clinical notes more available for research, but applications to stressful life events remain limited, leaving their documentation patterns and prognostic value understudied. By applying NLP, we identified stressful life events from clinical notes and examined their associations with mental disorde

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