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medRxiv PreprintsInternational10 November 2026

Streamlined Point-of-Care Ultrasound Examination for Pulmonary Tuberculosis

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Background: Point-of-care ultrasound (POCUS) is a low-cost, radiation-free triage tool but lacks standardized acquisition protocols for tuberculosis (TB). We developed and evaluated a streamlined symmetric POCUS protocol for pulmonary TB in a high-burden setting. Methods: Ugandan participants aged [≥]13 years with confirmed pulmonary TB, household TB exposure, or a non-TB respiratory condition underwent an 18-position POCUS examination (12 lung zones and 6 pre-established extrapulmonary positions). Random Forest classifiers using prespecified pathologic features were developed in a fixed st
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