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medRxiv PreprintsInternational9 November 2026

Regression-Based Balance Discordance Refines Prediction of Prospective Falls After Subacute Stroke: A Secondary Analysis of the LEAPS Trial

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Objective: To determine whether continuous, regression-based measures of balance discordance refine prediction of prospective, recurrent falls after subacute stroke relative to a previously published threshold-based classification in the same cohort, and to characterize how a purely data-driven, dimensionality-reduction-based composite expresses the same underlying measures. Design: Secondary, observational analysis of a randomized controlled trial. Recurrent falls were modeled using Andersen-Gill Cox proportional hazards regression with robust standard errors clustered by participant. Setting
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