Patterns of Childhood Exposomes, White Matter Development and Behaviors Link to Future Cognition and Psychopathology in Youth

Environmental exposures during childhood strongly impact individuals' cognitive and socioemotional development, and psychiatric vulnerability. However, childhood exposures rarely occur in isolation. Instead, they form a highly correlated 'exposome' whose multidimensional relationships with brain development and behavioral outcomes remain poorly understood. Elucidating the complex interplay between brain, behavior, and environment requires a multivariate approach. This study used regularized multiset canonical correlation analysis on longitudinal data from 8,113 preadolescents in the Adolescent

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