Near point of care C-Reactive Protein and Serum Amyloid-A Test met WHO target product profile for TB screening

Background: TB eradication strategies in high burden countries need affordable, scalable, and accessible screening tools. This study investigated the diagnostic accuracy of C-reactive protein (CRP), serum amyloid A (SAA), and interferon gamma-induced protein 10 (IP-10) as potential screening tools. Methods. This cross-sectional diagnostic study investigated stored archived serum samples from three groups of subjects; bacteriology confirmed symptomatic TB group (n=57), probable TB (n=56) and healthy controls (n=60). CRP and SAA concentrations were measured using near point-of-care fluorescence

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