MLX-Radiomics: accelerating standardized regional and voxel-wise radiomics for CT, PET and MRI

Background: Differences among radiomics implementations complicate cross-study comparisons, while voxel-wise feature extraction remains computationally demanding. We developed MLX-Radiomics to accelerate regional feature extraction and voxel-wise mapping while preserving agreement with standardized reference measurements. Methods: MLX-Radiomics implements 172 feature definitions from the Image Biomarker Standardization Initiative (IBSI), 16 extensions and the IBSI 2 image filters. We assessed agreement with IBSI reference data and evaluated numerical accuracy against independent double-precisi

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