Histological characteristics of the quadriceps muscle and their associations with gait in older adults

Background/objective: There is a paucity of data about muscle morphology in aging adults. We quantified histologic features of the quadriceps muscle and examined their associations with gait function and physical activity in community-dwelling older adults. Methods: Participants were from the Rush Memory and Aging Project. Postmortem sections of the quadriceps muscles were examined by immunohistochemistry using antibodies against myosin heavy chain, and histological characteristics of the quadriceps muscles were derived through images quantifications and segmentations. In addition, brain secti

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