Harmonization of microbiome data in the Environmental influences on Child Health Outcomes (ECHO) Cohort to analyze environmental influences on the child microbiome

The human microbiome is critical for health across the life course and may mediate the relationship between early-life exposures and health outcomes. The Environmental influences on Child Health Outcomes (ECHO) Cohort provides a unique opportunity to investigate this relationship in children. Individual cohort sites within the ECHO Cohort collected and sequenced microbiome data prior to the consortium formation. Sequencing data were annotated using a common protocol. We summarized the relationship between participant characteristics and features of the microbiome to understand how ECHO can adv

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