Generative AI Versus Primary Care Physicians from Plan Initiation to Long-Term Maintenance of Chronic Disease Self-Management: A Vignette-Based Validation Study

Background Generative artificial intelligence (GenAI) may provide personalised and dynamically adjustable support for chronic disease self-management. However, previous studies have largely focused on isolated questions and a limited range of evaluation dimensions. Objective To compare the quality of self-management advice generated by GenAI and primary care physicians (PCPs) across multiple stages of chronic disease management and evaluation dimensions. Methods We conducted a cross-sectional, source-blinded comparative evaluation using 15 standardised vignettes of diabetes and hypertension de

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