medRxiv PreprintsInternational12 November 2026
Galantamine for routine neuromuscular block reversal and treatment of emergence delirium in children after ENT surgery: a retrospective observational study
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Background. Emergence delirium is a common complication of general anesthesia in children. Preschool age and ear, nose and throat (ENT) procedures are risk factors [1, 2, 3, 4]. The hypothesis linking delirium to central cholinergic deficiency provides a rationale for studying galantamine, an acetylcholinesterase inhibitor that crosses the blood-brain barrier and is used to reverse neuromuscular blockade. We assessed the association between its routine administration and emergence delirium in children after ENT surgery under sevoflurane anesthesia. Objective. To compare emergence delirium freq
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