Functional connectivity of reward and cognitive control networks predicts body mass index but not binge eating disorder in women

Background Binge eating disorder (BED) is associated with obesity as well as behavioral and neurobiological changes in the reward and cognitive control systems of the brain. To better dissociate neural mechanisms of pathological eating behavior, functional connectivity (FC) analyses have shown promise. However, there is currently no replicable signature of BED derived from fMRI. Methods We investigated FC in 61 women with varying symptoms of binge eating. The three groups included 21 women with BED, 20 women with subsyndromal BED (subBED), and 20 controls without binge eating (noBE) matched in

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