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medRxiv PreprintsInternational9 November 2026

Feasibility of Vibrotactile P50 Sensory-Gating Assessment Using Portable EEG

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Sensory gating (SG), most commonly quantified using the auditory P50 event-related potential elicited by a paired "double-click" paradigm, is a well-established biomarker of early sensory inhibition that reflects the brain's ability to suppress responses to repetitive sensory input. Although auditory SG paradigms have been widely used in both research and clinical settings, they impose an unavoidable auditory load and are generally limited to controlled laboratory environments, reducing their suitability for ecological monitoring and applications in which auditory resources must remain availab
Source: medRxiv Preprints
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