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medRxiv PreprintsInternational12 November 2026

Factors associated with congenital syphilis among women with gestational syphilis in a public health network in Bogota, Colombia, 2017-2024: A case-control study

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Background Congenital syphilis remains a preventable cause of perinatal morbidity and mortality, and its incidence in Colombia remains well above the elimination target. We aimed to identify maternal and prenatal care factors associated with congenital syphilis among women with gestational syphilis attended in a public health network serving socially vulnerable populations in Bogota, Colombia. Methods We conducted a retrospective case-control study using surveillance and clinical records from the Subred Integrada de Servicios de Salud Sur E.S.E. for pregnancies ending between 2017 and 2024. Ca
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