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medRxiv PreprintsInternational11 November 2026

Decision for hysterectomy as a modifiable cardiovascular risk factor: A systematic review and meta-analysis

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Objective: To describe the role of hysterectomy in modifying the major atherosclerotic cardiovascular disease risk factors. Data sources: PubMed, Cochrane Library, Embase, and ScienceDirect were searched from database inception to March 10, 2026. Study eligibility criteria: Full-text randomized controlled trials, case-control studies, cross-sectional studies, cohort studies, case series, and experimental studies reporting new-onset cardiovascular events, diabetes mellitus, hypertension, dyslipidemia, or other metabolic effects following hysterectomy were eligible. Reviews and book chapters wer
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