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medRxiv PreprintsInternational8 November 2026

Computational Modeling of the Acoustic Radiation Force and Viscoelastic Displacement for Transcranial Focused Ultrasound Neuromodulation

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Objective: In transcranial ultrasound neuromodulation (TUS), simulations of the harmonic pressure are often used for treatment planning. However, other mechanisms of energy transfer, such as acoustic radiation force (ARF) and the resulting tissue displacement, are reported less frequently. Furthermore, there is limited guidance on how these mechanisms should be simulated. This study evaluates the numerical convergence and accuracy of different ARF formulations and investigates the simulation of ultrasound-induced tissue displacement in the context of TUS. Approach: Two simulations steps are us
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