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medRxiv PreprintsInternational12 November 2026

Associations between different intensities of leisure-time physical activity and subsequent psychotropic medication use among young and early midlife adults: a register-linked follow-up study

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Introduction Previous studies have not examined associations between physical activity intensity and subsequent psychotropic medication use. We examined associations between different leisure-time physical activity (LTPA) intensities and subsequent psychotropic medication purchases. Methods We used Helsinki Health Study questionnaire data collected in 2017 from 19-39-year-old employees of the City of Helsinki, linked to register data on psychotropic medication purchases from 2014 to 2022 (82.5% consented to the register linkage). The analytical sample included 4,160 participants (80.4% women,
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