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medRxiv PreprintsInternational6 November 2026

Tremor Morphology Toolkit: Waveform Modulation-Based Tremor Phenotyping

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Clinicians typically characterize tremor by its frequency, amplitude, and body region affected. Other aspects also provide critical clues to the type of tremor and its underlying pathophysiology including tremor waveform morphology, consistency across cycles, and variability in amplitude and timing. We introduce the Tremor Morphology Toolkit (TMT), an eight metric, waveform derived panel that quantifies these features from upper limb inertial signals. Using accelerometer and gyroscope recordings from 34 individuals with upper-extremity tremor across four standardized tasks (rest, outstretched,
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