The Complex Interplay Between Cancer and the Lung Microbiome

Background: The lung fosters a diverse microbiome that may have a complex interplay with underlying diseases, such as lung cancer. However, existing literature has revealed diverse results, likely owing to small sample sizes and diverse sampling methods. In this context, we aim to characterize the lung microbiome and its association with malignancy via multiple sampling methods during lung resection. Methods: Patients undergoing lung resection for confirmed malignancy were prospectively included in the study. During the operation, a bronchial swab and a parenchymal biopsy of lung tissue were c

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