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medRxiv PreprintsInternational30 October 2026

Short-Lived Hyperglycaemia Contributes to Continuous Glucose Monitoring Metrics Used for Therapeutic Decision-Making

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Background: Continuous glucose monitoring (CGM) metrics, including time in range (TIR) and median glucose, guide therapeutic decisions in type 1 diabetes (T1D) but do not distinguish sustained from transient hyperglycaemia. We investigated the prevalence of short-lived hyperglycaemia (SLH), i.e. brief isolated hyperglycaemic episodes, and its contribution to CGM metrics in T1D children and adolescents. Methods: In this single-centre retrospective cohort study, T1D patients aged 6 months-20 years, enrolled in 2025-2026, with 5-minute CGM data, >=70% coverage and median glucose 6.1-9.4 mmol/L wi
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