Sacral nerve stimulation is more efficient in facilitating pelvic floor responses than pudendal nerve stimulation

Introduction: Sacral neuromodulation (SNM) is a third line treatment for pelvic organ dysfunction. Pudendal nerve stimulation (PNS) uses SNM electrode leads in an off-label fashion to also treat pelvic dysfunction. Differences in how stimulation of these two nerve targets activates the urethra and external anal sphincter (EAS) may provide insights into the mechanisms of these therapies. Materials and Methods: During SNM lead implant surgeries, needle electrodes and a high-resolution manometry catheter were used to record EAS electromyography (EMG) and multi-segment urethra pressure, respective

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