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medRxiv PreprintsInternational6 November 2026

Routine CBC-Derived Markers of Systemic Inflammation Are Associated With Growth of the Dilated Ascending Aorta During CT Surveillance

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Background: Ascending aortic surveillance relies on diameter thresholds, yet most dissections occur below them. Inflammation drives aortic wall remodeling independent of diameter. Inflammation drives aortic wall remodeling independent of diameter. Inflammatory indices derived from routine blood counts, such as neutrophil-to-lymphocyte ratio (NLR), red cell distribution width (RDW), and systemic immune-inflammation index (SII) have been show to predict adverse cardiovascular outcomes, but their association with ascending aortic growth is unclear. Methods and Results: We retrospectively studied
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