Repeatability and reproducibility of spectral results with clinical photon-counting CT: multi-center phantom study

Background: Photon-counting CT utilizes a new detector technology that enhances quantitative imaging but introduces new system sensitivities that may affect quantitative reproducibility. For biomarkers, this quantitative reproducibility across protocol parameters, between institutions, and over time boosts their generalizability and clinical adoption for improved disease stratification. While stability across protocol parameters and over time have previously been evaluated, inter-institution reproducibility with PCCT remains unknown. Purpose: This study aimed to evaluate the repeatability and

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