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medRxiv PreprintsInternational8 October 2026

Refining E-detectioN Tools for Emerging mental disoRders (ENTER) to identify young people at clinical high risk for psychosis in the community: model development and internal validation

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Early detection of individuals at clinical high risk for psychosis (CHR-P) improves access to preventive care. We developed and internally validated the E-DetectioN Tool for Emerging mental disoRders (ENTER), a multimodal digital screener designed to improve community identification of CHR-P compared with an established approach (PQ-16 cut-off). Participants aged 12-35 years from the UK and Italy completed the online ENTER screener, assessing attenuated psychotic symptoms, processing speed and environmental risk factors. Participants above the PQ-16 cut-off and a random subset below were asses
— medRxiv Preprints
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