Quantitative CTA-Based Carotid Plaque Composition Across Stroke Etiologies and Residual Vascular Risk

Background: Carotid plaque vulnerability features may provide prognostic information beyond luminal stenosis, but the value of quantitative plaque composition on CTA remains unclear. Objectives: We investigated whether plaque composition analysis in routine CTA in patients with ischemic stroke or TIA can identify high-risk plaques across etiologies, particularly among strokes of undetermined etiology and predict residual vascular risk. Methods: We analyzed carotid CTAs from 314 patients with acute ischemic stroke or TIA. CTA-derived plaque composition was quantified using commercially availabl

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