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medRxiv PreprintsInternational3 November 2026

PROSPECTIVE COMPARISON OF OPTIMIZED COMPRESSED SENSING AND GRAPPA-ACCELERATED 3D-TOF-MRA FOR EVALUATION OF UNTREATED INTRACRANIAL ANEURYSMS AT 1.5 T: A NON-INFERIORITY STUDY

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RATIONALE AND OBJECTIVES 3D-TOF-MRA is a standard non-invasive method for detecting and monitoring intracranial aneurysms, but long scan times remain a limitation. Compressed sensing (CS) acceleration for intracranial aneurysm evaluation has mainly been studied at 3T. This prospective single-center non-inferiority study compared CS-accelerated 3D-TOF at 1.5T with GRAPPA-accelerated 3D-TOF-MRA for evaluating untreated intracranial aneurysms. MATERIALS AND METHODS Sample size was determined via a preliminary retrospective study. 25 patients with 32 untreated aneurysms underwent both CS- (factor
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