Post-psychedelic and meditation-related challenges: a protocol for a mixed-methods longitudinal-observational study

Introduction: Psychedelics and meditation are increasingly used for therapeutic and wellness purposes. However, research into adverse effects (AEs) has been limited, without adequate investigation of the nature, clinical characteristics, and diversity of persisting challenges following psychedelic use and meditation practice. This study aims to better characterize the clinical and contextual features of these challenges, describe their longitudinal course, and compare psychedelic-related challenges to meditation-related challenges, selected as comparator conditions given previously characteriz

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