medRxiv PreprintsInternational4 November 2026
Pediatric Influenza Vaccine Effectiveness Against Emergency Visits and Hospitalization in Canada: 2024-2025 and 2025-2026 seasons
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Importance: Influenza causes substantial morbidity in children, yet Canadian data on influenza vaccine effectiveness (VE) in preventing emergency department (ED) visits and hospitalizations are limited. Objective: To estimate VE against influenza-associated ED visits and hospitalizations among children during the 2024-2025 and 2025-2026 seasons. Design: Test negative case control design. Setting: Fourteen Canadian pediatric tertiary-care hospitals participating in the Surveillance Program for the Rapid IdeNtification and TracKing of Infectious Diseases in kidS (SPRINT KIDS) network. Participan
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