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medRxiv PreprintsInternational5 November 2026

Peak Agricultural Pesticide Spray Periods are related to Real-World Cognition Using an Ecological Momentary Assessment Burst Design over Two Years

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Objective: Emerging evidence suggests that exposure to organophosphate, neonicotinoid, and other pesticides may transiently impair cognition; however, traditional "snapshot" laboratory-based cognitive assessments fail to capture fluctuations in cognitive performance. This study used ecological momentary cognitive testing (EMCT) to evaluate whether real-world cognitive performance differs between peak and low floricultural pesticide spray seasons, thereby evaluating the potential cyclical effects of agricultural production and related pesticide exposures. Material and Methods: From 2022 to 2024
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