Interval colorectal cancer risk by haemoglobin concentration in Australia's National Bowel Cancer Screening Program

Background Interval colorectal cancers (CRCs) are an important measure of screening performance. We assessed interval CRC risk after negative faecal immunochemical testing (FIT), its association with faecal haemoglobin (f-Hb) concentration, and differences by age and sex in Australia s National Bowel Cancer Screening Program (NBCSP). Methods We conducted a population-based retrospective cohort study linking Queensland screening and cancer registry records for NBCSP participants aged 50-74 years screened in 2018-2022. Eligible episodes had f-Hb below 20 ug/g in both samples. We excluded episode

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