medRxiv PreprintsInternational8 October 2026
Increased sensitivity of detecting variation in malaria endemicity by parasite density measurement in large surveys
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Introduction: The continuing high and inequitable global malaria burden requires improved methods to understand trends and target control. Current methods often involve infection prevalence surveys, but additional parasitological measures could increase precision in estimating infection burdens of communities. Methods: Focusing on the country with most malaria globally, examinations of slides from 10,651 children under five sampled in the 2021 national Malaria Indicator Survey in Nigeria were performed to measure asexual parasite densities in infected children and discriminate sexual stages an
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