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medRxiv PreprintsInternational3 November 2026

Generation-time distortion is an emergent property of epidemic control

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We find that a vast space of public health interventions necessarily reshape the intervals between successive infections, known as generation times, for directly-transmitted infectious diseases (e.g., COVID-19, Ebola virus, influenza). While some studies have connected specific interventions (e.g., contact-tracing, isolation) to shifted generation times, most epidemiological analyses assume these intervals are stationary. We reveal that this assumption is substantially more fragile than previously recognised. We develop a universal microscopic representation for all intervention mechanisms tha
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