First-trimester nocturnal cardiorespiratory coupling during home sleep testing and later pregnancy complications: a secondary analysis of the nuMoM2b cohort

We tested whether direction-specific nocturnal cardiorespiratory coupling (CRC) in the first trimester differed in pregnancies that later developed obstetric complications. The analysis included 2504 nulliparous women from the nuMoM2b cohort with valid level 3 home sleep recordings at 6-13 weeks' gestation. Bidirectional CRC between RR intervals and abdominal respiratory effort was quantified using bivariate phase-rectified signal averaging in consecutive 5-min segments. Coupling strength, local transition dynamics, and waveform irregularity were summarized by nightly mean and standard deviati

This content is for informational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Consult a healthcare professional before starting any supplement, treatment, or program: especially if you are pregnant, nursing, taking medication, or managing a health condition.