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medRxiv PreprintsInternational5 November 2026

Figure format and the accuracy of AI-assisted reconstruction of Kaplan-Meier survival data

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Reconstructing participant-level data from published Kaplan-Meier curves supports meta-analysis and other secondary survival analyses when original trial records are unavailable. Researchers may use original PDF figures or screenshots, which can look alike but retain different information. We assessed how converting vector figures to images affects reconstruction by a language model that can inspect files and execute code. We generated 64 independent two-arm datasets across four scenarios combining 100 or 1,000 participants per arm with proportional or crossing hazards. Each figure was supplie
Source: medRxiv Preprints
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