Fasting plasma fructose is associated with postprandial ethanol levels and mitochondrial dysfunction: linking fasting fructose to MASLD

High dietary fructose consumption is a recognized risk factor for metabolic dysfunction-associated steatotic liver disease (MASLD), but the clinical relevance of fasting fructose levels remains unexplored. This study investigated gut microbiota and hepatic transcriptional alterations associated with fasting fructose levels and their potential link to MASLD. We analyzed data from a subset of 49 morbidly obese individuals enrolled in the prospective BARIA cohort. Fasting plasma fructose levels were significantly higher in individuals with MASLD and were associated with polyol pathway downregulat

This content is for informational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Consult a healthcare professional before starting any supplement, treatment, or program: especially if you are pregnant, nursing, taking medication, or managing a health condition.