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medRxiv PreprintsInternational30 October 2026

Exploratory Symptom Profiles and Clinical Correlates in Adults with Attention-Deficit/Hyperactivity Disorder: A Retrospective Study Using the Wender-Reimherr Adult Attention Deficit Disorder Scale

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Background: Emotional dysregulation (ED) is a clinically relevant feature of adult attention-deficit/hyperactivity disorder (ADHD), but its relationship to clinical burden remains incompletely characterized. We aimed to describe latent symptom profiles and compare clinical and sociodemographic characteristics of adults assigned to classes with elevated probabilities in emotion-related domains with those assigned to the remaining classes. Methods: This retrospective cross-sectional study included 749 adults with ADHD from a specialized outpatient clinic. Latent class analysis was performed on 2
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