Evaluation of a Targeted Oral Microbiome Treatment in an Older Adult Population

Gingivitis is highly prevalent among older adults and is associated with systemic diseases. Accessible and effective interventions are needed, particularly for underserved populations facing barriers to conventional dental care, such as older adults. This study evaluated the efficacy of a novel, multi-component lozenge (PTx800) designed to modulate the oral environment through blockade of sugar-to-acid and sugar-to-biofilm production of the oral microbiota. A six-week, double-blind, randomized, active placebo-controlled pilot trial was conducted with older adults (final sample n=20) residing i

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