Epilepsy Lateralization by Elastic Net Regularization of a Diffusion Tensor Imaging Biomarker using Machine Learning

Objective: Accurate lateralization of the epileptogenic focus is essential for presurgical evaluation of patients with drug-resistant epilepsy. This study examined whether diffusion tensor imaging (DTI) measures of white matter microstructure, combined with clinical and demographic variables, could classify epilepsy lateralization using machine learning. Methods: We present a retrospective analysis of 334 adult patients undergoing presurgical epilepsy evaluation at the University of Kansas Health System. Fractional anisotropy (FD) and mean diffusivity (MD) were extracted from 36 bilateral whit

This content is for informational purposes only and is not medical advice. It is not intended to diagnose, treat, cure, or prevent any disease. Consult a healthcare professional before starting any supplement, treatment, or program: especially if you are pregnant, nursing, taking medication, or managing a health condition.