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medRxiv PreprintsInternational5 November 2026

Epidemiology of acute respiratory infections in adult patients in Hospices Civils de Lyon, France, between October 2016 and April 2025

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Background Multiple viruses can cause acute respiratory infections (ARI), impacting morbidity, mortality and hospital resources. The objective of this study was to describe viral circulation among patients with ARI, patients characteristics and severity outcomes. Methods A retrospective cohort was assembled using electronic health records from the Hospices Civils de Lyon, France. Adult patients ([≥]18 years) hospitalised or presenting to the emergency department from October 2016 to April 2025 with either an ICD-10 diagnostic code for ARI or a laboratory-confirmed viral detection were inclu
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