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medRxiv PreprintsInternational8 October 2026

Effects of cognitive-behavioural therapy for insomnia on cognitive and emotional functioning in adults with insomnia: behavioural and neuroimaging evidence

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Study Objectives: To characterize neural correlates of memory and emotion reactivity in individuals with insomnia disorder (INS) compared to good sleepers (GS) and to investigate associated short- and long-term changes following cognitive-behavioural therapy for insomnia (CBTi). Methods: This randomized controlled trial included 56 INS and 20 GS. At baseline, participants underwent resting-state and task-based functional magnetic resonance imaging, including working memory, emotion reactivity, and face-name associative memory tasks. They filled out sleep diaries and self-report questionnaires
— medRxiv Preprints
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