Effect of food-cues on aMCC glutamate modulation during inhibitory control post weight loss intervention: a 1H fMRS study

Objective: Poor inhibitory control may decrease weight loss maintenance. The neurobiological mechanisms are poorly understood. We investigated whether glutamate modulation in the anterior mid-cingulate cortex (aMCC) during response inhibition is impacted by food-cues and associated with self-reported behaviors and weight loss maintenance. Methods: 27 adults with overweight/obesity were recruited from a clinical weight management program. 1H fMRS (midline aMCC) was acquired during a visual-guided response inhibition task engaging two responding modes [non-selective (100% responses) or selective

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