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medRxiv PreprintsInternational2 November 2026

Do Sleep Questionnaires Add Predictive Value Beyond Demographics for Obstructive Sleep Apnea Severity? Evidence from 67,397 Patients

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Background: Sleep questionnaires are widely used to screen for obstructive sleep apnea (OSA), but their incremental value beyond collecting basic demographics is rarely assessed. Using a large sample of sleep clinic intake questionnaire data that includes the Epworth Sleepiness Scale, questions on snoring and breathing pause as well as medical history data, we quantified questionnaire-item contributions relative to demographics for OSA severity classification. Methods: In a retrospective cohort of 67,397 adults referred for in-laboratory polysomnography and with questionnaire data, XGBoost cla
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